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Immunological status of maculoanaesthetic leprosy: leucocyte migration inhibition test as a measure of cell mediated immune response.

Sambasiva Rao, Praveen R. Rao

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Abstract

M. leprae-specific cell-mediated immune responses were studied in 36 Maculoanaesthetic (MA) leprosy patients using Leucocyte Migration Inhibition Test (LMIT). 21-Tuberculoid, 13-Indeterminate, 16-Borderline, 13-Lepromatous and 20-Healthy controls were also studied for comparison. Highly significant differences (p less than 0.001) in the mean Migratory Indices (M.I.) were found between MA leprosy type and each of the other leprosy type or control group. The results support the concept that MA type forms a distinct form of leprosy from tuberculoid type or any other type of leprosy.

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What this paper is about

M. leprae-specific cell-mediated immune responses were studied in 36 Maculoanaesthetic (MA) leprosy patients using Leucocyte Migration Inhibition Test (LMIT). 21-Tuberculoid, 13-Indeterminate, 16-Borderline, 13-Lepromatous and 20-Healthy controls were also studied for comparison. Highly significant differences (p less than 0.001) in the mean Migratory Indices (M.I.) were found between MA leprosy type and each of the other leprosy type or control group. The results support the concept that MA type forms a distinct form of leprosy from tuberculoid type or any other type of leprosy.

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Available abstract

M. leprae-specific cell-mediated immune responses were studied in 36 Maculoanaesthetic (MA) leprosy patients using Leucocyte Migration Inhibition Test (LMIT). 21-Tuberculoid, 13-Indeterminate, 16-Borderline, 13-Lepromatous and 20-Healthy controls were also studied for comparison. Highly significant differences (p less than 0.001) in the mean Migratory Indices (M.I.) were found between MA leprosy type and each of the other leprosy type or control group. The results support the concept that MA type forms a distinct form of leprosy from tuberculoid type or any other type of leprosy.

Key concepts: Leprosy, Tuberculoid leprosy, Medicine, Immune system, Immunology, Lepromatous leprosy, Mycobacterium leprae, Cell mediated immunity

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Immunological status of maculoanaesthetic leprosy: leucocyte migration inhibition test as a measure of cell mediated immune response. — Research Paper | ScholarLens