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2016•HaematologicaOpen access

Impaired formation of erythroblastic islands is associated with erythroid failure and poor prognosis in a significant proportion of patients with myelodysplastic syndromes

Guntram Buesche, H. Teoman, Aristoteles A. N. Giagounidis, Gudrun Göhring, Brigitte Schlegelberger, Arnold Ganser, C. Aul, Hans Heinrich Kreipe

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Abstract

Erythropoiesis is arranged in erythroblastic islands (Ery-Is),[1][1] the specialized niche known for more than 50 years[2][2] in which erythroid precursors proliferate and differentiate. However, the significance of erythropoiesis in anemia, the leading symptom of myelodysplastic syndromes (MDS),

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What this paper is about

Erythropoiesis is arranged in erythroblastic islands (Ery-Is),[1][1] the specialized niche known for more than 50 years[2][2] in which erythroid precursors proliferate and differentiate. However, the significance of erythropoiesis in anemia, the leading symptom of myelodysplastic syndromes (MDS),

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Available abstract

Erythropoiesis is arranged in erythroblastic islands (Ery-Is),[1][1] the specialized niche known for more than 50 years[2][2] in which erythroid precursors proliferate and differentiate. However, the significance of erythropoiesis in anemia, the leading symptom of myelodysplastic syndromes (MDS),

Key concepts: Myelodysplastic syndromes, Medicine, Internal medicine, Hematology, Oncology, Bone marrow

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Impaired formation of erythroblastic islands is associated with erythroid failure and poor prognosis in a significant proportion of patients with myelodysplastic syndromes — Research Paper | ScholarLens