The Result of Transrectal Ultrasound Guided 10-14 Cores Biopsies of the Prostate

Introduction The diagnostic tool in prostate cancer is prostate biopsy but recently classic biopsy has low efficacy. In recent years, trans-rectal ultrasound guided prostate biopsy is a standard method in prostate cancer diagnosis. In the present study, we report our experience about ultrasound guided 10-14 core prostate biopsies at a hospital in Mashhad. Materials and Methods The study included 196 men with PSA values of �10 ng/ml or 10 ng/ml �PSA level �4 ng/ml and Free PSA/ Total PSA ratio was less than 20. These patients underwent transrectal ultrasound (TRUS)-guided 10-14 core prostate biopsy. Results Of the 196 patients, cancer in 73 patients (37.2), intraepithelial neoplasia in 14 patients (7.1) and benign prostatic hyperplasia in 108 patients (55.1) were diagnosed. Transrectal ultrasound guided 10-14 core prostate biopsy diagnosed prostatic cancer in 25 of 14 patients who had no prostatic cancer with traditional biopsy. There were non significant associations between age and total and free PSA. There was a non significant correlation between the free PSA and Gleason score, but there was a significant correlation between the Gleason score and total PSA. Conclusion This study shows that the TRUS-guided 10-14 core biopsies yield a better prostate cancer detection rate than the classic biopsy.