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2013•CARDIOVASCULAR THERAPY AND PREVENTIONOpen access

DIURETIC-BASED COMBINATION THERAPY IN PATIENTS WITH ARTERIAL HYPERTENSION: RESULTS OF THE RUSSIAN TRUST STUDY

Н. Е. Гаврилова, Р. Г. Оганов

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Abstract

Arterial hypertension (AH) is one of the most important problems of the modern medicine, due to its exceptionally high prevalence. This study focused on effectiveness and safety of the diuretic-based combination therapy among patients aged >18 years (1476 men and 2989 women) with a clinical diagnosis of Stage 1–3 AH. All patients received fixed-dose combination therapy with atenolol and chlorthalidone. The findings from the TRUST study have confirmed safety and effectiveness of the fixed-dose combination of atenolol and chlorthalidone.

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What this paper is about

Arterial hypertension (AH) is one of the most important problems of the modern medicine, due to its exceptionally high prevalence. This study focused on effectiveness and safety of the diuretic-based combination therapy among patients aged >18 years (1476 men and 2989 women) with a clinical diagnosis of Stage 1–3 AH. All patients received fixed-dose combination therapy with atenolol and chlorthalidone. The findings from the TRUST study have confirmed safety and effectiveness of the fixed-dose combination of atenolol and chlorthalidone.

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Available abstract

Arterial hypertension (AH) is one of the most important problems of the modern medicine, due to its exceptionally high prevalence. This study focused on effectiveness and safety of the diuretic-based combination therapy among patients aged >18 years (1476 men and 2989 women) with a clinical diagnosis of Stage 1–3 AH. All patients received fixed-dose combination therapy with atenolol and chlorthalidone. The findings from the TRUST study have confirmed safety and effectiveness of the fixed-dose combination of atenolol and chlorthalidone.

Key concepts: Chlorthalidone, Medicine, Atenolol, Diuretic, Combination therapy, Internal medicine, Cardiology, Fixed-dose combination

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DIURETIC-BASED COMBINATION THERAPY IN PATIENTS WITH ARTERIAL HYPERTENSION: RESULTS OF THE RUSSIAN TRUST STUDY — Research Paper | ScholarLens