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1988•Scandinavian Journal of Plastic and Reconstructive SurgeryRequires access

Silicon in Human Breast Tissue Surrounding Silicone Gel Prostheses: A Scanning Electron Microscopy and Energy Dispersive X-ray Investigation of Normal, Fibrocystic and Peri-prosthetic Breast Tissue

Ole Winding, L. O. D. Christensen, J. L. Thomsen, Marianne Nielsen, Vibeke Breiting, B Brandt

Open publisher page 46 citations

Abstract

Implanted silicone breast prostheses leak silicone gel through the intact membrane. In order to determine the exact location and to achieve a semiquantitative estimation of the amount of silicone in the surrounding tissue, a method involving scanning electron microscopy (SEM) and energy dispersive analysis of X-rays (EDAX) was used. By this method we were able to demonstrate the presence of the element silicon (Si) (main component of silicone, a polymer with a general formula e.g. (CH3[Si(CH3)2O]n Si(CH3)3 along the inner border of vacuoles corresponding to the light microscopic localization of droplets and in macrophages. The tissue adjacent to the prostheses had a higher silicon content than the control tissue.

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What this paper is about

Implanted silicone breast prostheses leak silicone gel through the intact membrane. In order to determine the exact location and to achieve a semiquantitative estimation of the amount of silicone in the surrounding tissue, a method involving scanning electron microscopy (SEM) and energy dispersive analysis of X-rays (EDAX) was used. By this method we were able to demonstrate the presence of the element silicon (Si) (main component of silicone, a polymer with a general formula e.g. (CH3[Si(CH3)2O]n Si(CH3)3 along the inner border of vacuoles corresponding to the light microscopic localization of droplets and in macrophages. The tissue adjacent to the prostheses had a higher silicon content than the control tissue.

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Available abstract

Implanted silicone breast prostheses leak silicone gel through the intact membrane. In order to determine the exact location and to achieve a semiquantitative estimation of the amount of silicone in the surrounding tissue, a method involving scanning electron microscopy (SEM) and energy dispersive analysis of X-rays (EDAX) was used. By this method we were able to demonstrate the presence of the element silicon (Si) (main component of silicone, a polymer with a general formula e.g. (CH3[Si(CH3)2O]n Si(CH3)3 along the inner border of vacuoles corresponding to the light microscopic localization of droplets and in macrophages. The tissue adjacent to the prostheses had a higher silicon content than the control tissue.

Key concepts: Silicone, Scanning electron microscope, Breast tissue, Silicon, Materials science, Wafer, Electron microscope, Biomedical engineering

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Silicon in Human Breast Tissue Surrounding Silicone Gel Prostheses: A Scanning Electron Microscopy and Energy Dispersive X-ray Investigation of Normal, Fibrocystic and Peri-prosthetic Breast Tissue — Research Paper | ScholarLens