Optimal Therapy for Polycythemia Vera and Essential Thrombocythemia: A Different Perspective
Richard T. Silver, Hans Carl Hasselbalch
Abstract
Richard T. Silver, Hans Carl Hasselbalch
Abstract
Recent publications have de-emphasized the importance of recombinant interferon alpha (rIFNα) for the treatment of polycythemia vera (PV) or essential thrombocythemia (ET), favoring the use of phlebotomy and/or hydroxyurea. Here we express our reasons for the use of rIFNα early in the course of PV or ET in the absence of a phase 3 trial.
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Recent publications have de-emphasized the importance of recombinant interferon alpha (rIFNα) for the treatment of polycythemia vera (PV) or essential thrombocythemia (ET), favoring the use of phlebotomy and/or hydroxyurea. Here we express our reasons for the use of rIFNα early in the course of PV or ET in the absence of a phase 3 trial.
Key concepts: Polycythemia vera, Phlebotomy, Essential thrombocythemia, Medicine, Alpha interferon, Perspective (graphical), Anagrelide, Internal medicine