2016•OncogeneOpen access

Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling

L Du, X Chen, Yu Qing Cao, Ling Lu, Fa-Chang Zhang, Sophia Bornstein, Y Li, Philip Owens, Stephen P. Malkoski, Sherif Said, F Jin, Molly F Kulesz-Martin, Neil D. Gross, X. J. Wang, S-L Lu

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Key concepts: Biology, Metastasis, Cancer research, PI3K/AKT/mTOR pathway, Head and neck squamous-cell carcinoma, Carcinogenesis, Protein kinase B, Epithelial–mesenchymal transition

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Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling — Research Paper | ScholarLens