1997•PhysiologyRequires access
GABAC Receptors: A Novel Receptor Family with Unusual Pharmacology
Enrico Cherubini, Fabrizio Strata
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Abstract
GABAC-receptor channels constitute a novel class of structurally defined receptors that are composed by the recently discovered r-subunits. They conduct chloride ions, are insensitive to both bicuculline and baclofen, and are blocked by picrotoxin. They are present in the hippocampus during development and in the retina where they play a crucial role in regulating visual processing.