ScholarLens Back to search
2014•PubMedRequires access

Cancer Antigen-125 as a marker of ascites in patients with liver cirrhosis.

Muhammad Omar Qureshi, Faisal Saud Dar, Nasir Khokhar

Open publisher page 14 citations

Abstract

OBJECTIVE: To evaluate the correlation between Cancer Antigen-25 (CA-125) levels with the amount of ascites in patients with liver cirrhosis. STUDY DESIGN: Observational, analytical study. PLACE AND DURATION OF STUDY: Shifa International Hospital, Islamabad, from March 2012 to February 2013. METHODOLOGY: A total of 130 patients with liver cirrhosis (with and without ascites) had serum CA-125 levels measured. The amount of ascites was classified according to physical examination and ultrasound (USG) findings. CA-125 levels were compared and correlated with amount of ascites. RESULTS: Majority of patients (57%) had hepatitis C virus and 60% were in class Child Pugh C. There was moderate correlation between amount of ascites and CA-125 levels (r = 0.642, p < 0.001) with significant raised levels of CA-125 in patients with ascites (p < 0.001). CONCLUSION: There was a moderate correlation between CA-125 levels and presence and amount of ascites.

About this research paper

What this paper is about

OBJECTIVE: To evaluate the correlation between Cancer Antigen-25 (CA-125) levels with the amount of ascites in patients with liver cirrhosis. STUDY DESIGN: Observational, analytical study. PLACE AND DURATION OF STUDY: Shifa International Hospital, Islamabad, from March 2012 to February 2013. METHODOLOGY: A total of 130 patients with liver cirrhosis (with and without ascites) had serum CA-125 levels measured. The amount of ascites was classified according to physical examination and ultrasound (USG) findings. CA-125 levels were compared and correlated with amount of ascites. RESULTS: Majority of patients (57%) had hepatitis C virus and 60% were in class Child Pugh C. There was moderate correlation between amount of ascites and CA-125 levels (r = 0.642, p < 0.001) with significant raised levels of CA-125 in patients with ascites (p < 0.001). CONCLUSION: There was a moderate correlation between CA-125 levels and presence and amount of ascites.

Why it matters

OpenAlex reports 14 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE: To evaluate the correlation between Cancer Antigen-25 (CA-125) levels with the amount of ascites in patients with liver cirrhosis. STUDY DESIGN: Observational, analytical study. PLACE AND DURATION OF STUDY: Shifa International Hospital, Islamabad, from March 2012 to February 2013. METHODOLOGY: A total of 130 patients with liver cirrhosis (with and without ascites) had serum CA-125 levels measured. The amount of ascites was classified according to physical examination and ultrasound (USG) findings. CA-125 levels were compared and correlated with amount of ascites. RESULTS: Majority of patients (57%) had hepatitis C virus and 60% were in class Child Pugh C. There was moderate correlation between amount of ascites and CA-125 levels (r = 0.642, p < 0.001) with significant raised levels of CA-125 in patients with ascites (p < 0.001). CONCLUSION: There was a moderate correlation between CA-125 levels and presence and amount of ascites.

Key concepts: Ascites, Cirrhosis, Medicine, Gastroenterology, Cancer antigen, Internal medicine, Cancer

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Cancer Antigen-125 as a marker of ascites in patients with liver cirrhosis. — Research Paper | ScholarLens