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2003•The American SurgeonRequires access

Treatment of Bleeding in Severe Hemorrhagic Pancreatitis with Recombinant Factor VIIa

Rob Schuster, Sarah J. Lee, Donald Rink

Open publisher page 11 citations

Abstract

Recombinant factor VIIa (rFVIIa) has been used to treat bleeding complications in patients with hemophilia. It acts at the site of vessel injury, forming a complex with tissue factor to activate the clotting cascade. Recent reports have shown rFVIIa may be a useful hemostatic agent in patients after obstetrical, urologic, trauma, or transplant procedures. We report the first documented case of bleeding from hemorrhage pancreatitis treated with rFVIIa.

About this research paper

What this paper is about

Recombinant factor VIIa (rFVIIa) has been used to treat bleeding complications in patients with hemophilia. It acts at the site of vessel injury, forming a complex with tissue factor to activate the clotting cascade. Recent reports have shown rFVIIa may be a useful hemostatic agent in patients after obstetrical, urologic, trauma, or transplant procedures. We report the first documented case of bleeding from hemorrhage pancreatitis treated with rFVIIa.

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OpenAlex reports 11 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Recombinant factor VIIa (rFVIIa) has been used to treat bleeding complications in patients with hemophilia. It acts at the site of vessel injury, forming a complex with tissue factor to activate the clotting cascade. Recent reports have shown rFVIIa may be a useful hemostatic agent in patients after obstetrical, urologic, trauma, or transplant procedures. We report the first documented case of bleeding from hemorrhage pancreatitis treated with rFVIIa.

Key concepts: Medicine, Recombinant factor VIIa, Factor VIIa, Pancreatitis, Hemostatics, Clotting factor, Surgery, Factor VII

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Treatment of Bleeding in Severe Hemorrhagic Pancreatitis with Recombinant Factor VIIa — Research Paper | ScholarLens