A comparative study of intrathecal Bupivacaine and Bupivacaine with Buprenorphine for post-operative analgesia in orthopedic surgeries

Introduction: Pain is a unique emotional experience, which is associated with actual or potential tissue damage. Postoperative pain management is necessary. The most effective preemptive analgesic regimens are those that are capable of limiting sensitization of the nervous system throughout the entire perioperative period. Material & Methods: Radomly patients were assigned in two groups of 60 patients who underwent lower limb orthopedic surgery. The clinical effects of intrathecally administered Inj Bupivacaine 0.5% hyperbaric 2.5 ml (group B) with Inj Buprenorphine preservative free 150 mcg additional to the hyperbaric bupivacaine 0.5% 2.5 ml (group B) for lower limb orthopedic surgeries were studied . Results: Surgery had mean duration of 87.3(16.7) min for group B and 96.3(17.1) min for group BN. There was statistically no significant (P>0.05) difference of time of onset, maximum level and time required reaching maximum level of sensory block in between the groups. All patients in both groups had complete motor blockade. There was statistically no significant (P>0.05) difference in preoperative, during surgery and postoperative hemodynamic parameters in between two groups. Sensory recovery was significantly (P