2010The FASEB JournalRequires access

Low dietary intake of vitamina B12 predicts hyperhomocysteinemia in Mexican women.

Miriam Aracely Anaya‐Loyola, Carina Alvarez, Jorge Luis Rosado Loría, Lindsay H. Allen

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Abstract

The objective of this cross‐sectional study was to evaluate the impact of diet on homocysteine (Hcy), vitamin B12 and folate status in women living in Queretaro (central Mexico). Average mean values for age, weight, height and BMI were 37.6±10.3 ys, 68.4 ± 14.6 kg, and 151.6±5.2 cm and 29.8±6.0 kg/m 2 , respectively. Mean concentrations of serum vitamin B12, folate and Hcy were 331.5±209.9 pmol/L, 21.1±8.2 nmol/L and 10.9±3.2 nmol/L. Vitamin B12 deficiency was observed in 11.4% of the participants. In addition 21.2% presented marginal status. Only 5.4% of the women were folate deficient. Prevalence of hyperhomocysteinemia was 32.6%. B12 deficient women had inadequate intakes of vitamin B12 in about 50% (

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What this paper is about

The objective of this cross‐sectional study was to evaluate the impact of diet on homocysteine (Hcy), vitamin B12 and folate status in women living in Queretaro (central Mexico). Average mean values for age, weight, height and BMI were 37.6±10.3 ys, 68.4 ± 14.6 kg, and 151.6±5.2 cm and 29.8±6.0 kg/m 2 , respectively. Mean concentrations of serum vitamin B12, folate and Hcy were 331.5±209.9 pmol/L, 21.1±8.2 nmol/L and 10.9±3.2 nmol/L. Vitamin B12 deficiency was observed in 11.4% of the participants. In addition 21.2% presented marginal status. Only 5.4% of the women were folate deficient. Prevalence of hyperhomocysteinemia was 32.6%. B12 deficient women had inadequate intakes of vitamin B12 in about 50% (

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Available abstract

The objective of this cross‐sectional study was to evaluate the impact of diet on homocysteine (Hcy), vitamin B12 and folate status in women living in Queretaro (central Mexico). Average mean values for age, weight, height and BMI were 37.6±10.3 ys, 68.4 ± 14.6 kg, and 151.6±5.2 cm and 29.8±6.0 kg/m 2 , respectively. Mean concentrations of serum vitamin B12, folate and Hcy were 331.5±209.9 pmol/L, 21.1±8.2 nmol/L and 10.9±3.2 nmol/L. Vitamin B12 deficiency was observed in 11.4% of the participants. In addition 21.2% presented marginal status. Only 5.4% of the women were folate deficient. Prevalence of hyperhomocysteinemia was 32.6%. B12 deficient women had inadequate intakes of vitamin B12 in about 50% (

Key concepts: Hyperhomocysteinemia, Vitamin B12, Homocysteine, Medicine, Internal medicine, Cyanocobalamin, Dietary Reference Intake, Vitamin

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