2016Open Journal of PathologyOpen access

The Use of Umbilical Stem Cells

Peter Cassar, Renald Blundell

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Abstract

The use of umbilical stem cells in tissue engineering is gaining in popularity. Some of the various uses of these umbilical stem cells are highlighted in this review, focusing mainly on their cartilage, bone and neuronal differentiating abilities. The review will also shed light on the application of these abilities in human clinical trials to repair, protect and treat diseases, e.g. neurodegenerative diseases such as Alzheimer’s and cerebral palsy. A side by side comparison with bone marrow mesenchymal stem cells (current gold standard for tissue engineering) will give a better idea of the viability and efficiency of umbilical stem cell use.

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What this paper is about

The use of umbilical stem cells in tissue engineering is gaining in popularity. Some of the various uses of these umbilical stem cells are highlighted in this review, focusing mainly on their cartilage, bone and neuronal differentiating abilities. The review will also shed light on the application of these abilities in human clinical trials to repair, protect and treat diseases, e.g. neurodegenerative diseases such as Alzheimer’s and cerebral palsy. A side by side comparison with bone marrow mesenchymal stem cells (current gold standard for tissue engineering) will give a better idea of the viability and efficiency of umbilical stem cell use.

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Available abstract

The use of umbilical stem cells in tissue engineering is gaining in popularity. Some of the various uses of these umbilical stem cells are highlighted in this review, focusing mainly on their cartilage, bone and neuronal differentiating abilities. The review will also shed light on the application of these abilities in human clinical trials to repair, protect and treat diseases, e.g. neurodegenerative diseases such as Alzheimer’s and cerebral palsy. A side by side comparison with bone marrow mesenchymal stem cells (current gold standard for tissue engineering) will give a better idea of the viability and efficiency of umbilical stem cell use.

Key concepts: Stem cell, Mesenchymal stem cell, Umbilical cord, Medicine, Adult stem cell, Bone marrow, Pathology, Neuroscience

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