1983•Agricultural and Biological ChemistryOpen access

Studies on ribocitrin, a new inhibitor of Streptococcus mutans dextransucrase. Part V. Effect of ribocitrin on glucan synthesizing enzymes of Streptococcus mutans E49.

Masachika Takashio, YOSHIRO OKAMI

Abstract

Enzymes participating in glucan synthesis by Streptococcus mutans E49 were separated into two fractions with distinctly different activities by chromatography on DEAE Bio-Gel A. The insoluble glucan (IG) was revealed to be formed by the coupling reaction of these two enzymes, dextransucrase (SGE), which synthesizes soluble glucan from sucrose, and a glucan insolubilizing e nzyme (IGE), which forms IG from soluble glucan.Ribocitrin was found to inhibit IG synthesis by inhibiting SGE.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Dextransucrase, Streptococcus mutans, Glucan, Chemistry, Enzyme, Sucrose, Dextran, Glucosyltransferases