2010•Unpublished venueRequires access

Global Hypothesis Test to Simultaneously Compare the Predictive Values of Two Binary Diagnostic Tests in Paired Designs: a Simulation Study

José Antonio Roldán Nofuentes, J. D. Luna del Castillo, Miguel Ángel Montero Alonso

Abstract

The positive and negative predictive values of a binary diagnostic test are measures of the clinical accuracy of the diagnostic that depend on the sensitivity and the specificity of the binary test and on the disease prevalence. Moreover, the positive predictive value and the negative predictive value are not parameters which are independent of each other. In this article, a global hypothesis test is studied to simultaneously compare the positive and negative predictive values of two binary diagnostic tests in paired designs.

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Available abstract

Key concepts: Predictive value, Positive predicative value, Diagnostic test, Statistics, Binary number, Test (biology), Value (mathematics), Mathematics