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Complex variant translocation t(1;2) with TPM3-ALK fusion due to cryptic ALK gene rearrangement in anaplastic large-cell lymphoma.

Reiner Siebert, Stefan Gesk, Lana L. Harder, Doris Steinemann, Werner Grote, Brigitte Schlegelberger, Markus Tiemann, Iwona Włodarska, Verena Schemmel

Open publisher page 49 citations

Abstract

To the Editor: Anaplastic large-cell lymphoma (ALCL) is frequently associated with the recurrent translocation t(2;5)(p23;q35) that results in activation of the anaplastic lymphoma kinase ( ALK ) gene at 2p23 by fusion to the ubiquitously expressed gene encoding the nucleolar phosphoprotein

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To the Editor: Anaplastic large-cell lymphoma (ALCL) is frequently associated with the recurrent translocation t(2;5)(p23;q35) that results in activation of the anaplastic lymphoma kinase ( ALK ) gene at 2p23 by fusion to the ubiquitously expressed gene encoding the nucleolar phosphoprotein

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OpenAlex reports 49 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

To the Editor: Anaplastic large-cell lymphoma (ALCL) is frequently associated with the recurrent translocation t(2;5)(p23;q35) that results in activation of the anaplastic lymphoma kinase ( ALK ) gene at 2p23 by fusion to the ubiquitously expressed gene encoding the nucleolar phosphoprotein

Key concepts: Anaplastic lymphoma kinase, Fusion gene, Chromosomal translocation, Anaplastic large-cell lymphoma, Gene rearrangement, Lymphoma, Biology, Cancer research

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Complex variant translocation t(1;2) with TPM3-ALK fusion due to cryptic ALK gene rearrangement in anaplastic large-cell lymphoma. — Research Paper | ScholarLens