2016•Toxicology in VitroRequires access

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer

Shalenie P. den Braver-Sewradj, Michiel W. den Braver, Nico Vermeulen, Jan N. M. Commandeur, Lysiane Richert, J. Chris Vos

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Key concepts: Metabolism, Drug metabolism, Chemistry, Sulfation, Cytochrome P450, Acetaminophen, Pharmacology, Biochemistry

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Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer — Research Paper | ScholarLens