The Anthelmintic Effect of Dithiazanine in Experimental Animals
Max C. McCowen, Maurice E. Callender, M. C. Brandt
Abstract
Max C. McCowen, Maurice E. Callender, M. C. Brandt
Abstract
SummaryA new anthelmintic compound, dithiazanine (3,3′diethylthiadicarbocyanine iodide), was found to be highly effective by oral administration against pinworms in mice, ascarids, hookworms, and whipworms in dogs, as well as ascarids and hookworms in cats.Further investigations are necessary to determine if dithiazanine is effective in the treatment of such human helminthic diseases as ascariasis, oxyuriasis, trichuriasis and strongyloidiasis.
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SummaryA new anthelmintic compound, dithiazanine (3,3′diethylthiadicarbocyanine iodide), was found to be highly effective by oral administration against pinworms in mice, ascarids, hookworms, and whipworms in dogs, as well as ascarids and hookworms in cats.Further investigations are necessary to determine if dithiazanine is effective in the treatment of such human helminthic diseases as ascariasis, oxyuriasis, trichuriasis and strongyloidiasis.
Key concepts: Anthelmintic, Ascariasis, Trichuriasis, Strongyloidiasis, Helminths, Oxyuriasis, Helminthiasis, Ascaris