1957American Journal of Tropical Medicine and HygieneRequires access

The Anthelmintic Effect of Dithiazanine in Experimental Animals

Max C. McCowen, Maurice E. Callender, M. C. Brandt

Open publisher page 22 citations

Abstract

SummaryA new anthelmintic compound, dithiazanine (3,3′diethylthiadicarbocyanine iodide), was found to be highly effective by oral administration against pinworms in mice, ascarids, hookworms, and whipworms in dogs, as well as ascarids and hookworms in cats.Further investigations are necessary to determine if dithiazanine is effective in the treatment of such human helminthic diseases as ascariasis, oxyuriasis, trichuriasis and strongyloidiasis.

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What this paper is about

SummaryA new anthelmintic compound, dithiazanine (3,3′diethylthiadicarbocyanine iodide), was found to be highly effective by oral administration against pinworms in mice, ascarids, hookworms, and whipworms in dogs, as well as ascarids and hookworms in cats.Further investigations are necessary to determine if dithiazanine is effective in the treatment of such human helminthic diseases as ascariasis, oxyuriasis, trichuriasis and strongyloidiasis.

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Available abstract

SummaryA new anthelmintic compound, dithiazanine (3,3′diethylthiadicarbocyanine iodide), was found to be highly effective by oral administration against pinworms in mice, ascarids, hookworms, and whipworms in dogs, as well as ascarids and hookworms in cats.Further investigations are necessary to determine if dithiazanine is effective in the treatment of such human helminthic diseases as ascariasis, oxyuriasis, trichuriasis and strongyloidiasis.

Key concepts: Anthelmintic, Ascariasis, Trichuriasis, Strongyloidiasis, Helminths, Oxyuriasis, Helminthiasis, Ascaris

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