STUDY ON COBALT-GREENPOLE. II. DISTRIBUTION OF Co$sup 60$-GREENPOLE IN THE LIVING BODY AND ITS EXCRETION

Intravenously injected Co/sup 6//sup 0/-greenpole in the white rats wss mostly distributed in the liver, spleen, and bone marrow (with the maximum value at 6 hours after injection), but less in the lung, intestine, and kidney (a maximum value at 3 hours after injection). Histologically and autoradiographically examined, the injected material was dem onstrated in the Kupffer cells of the liver, in reticulum cells of the spleen, and in the large phagocytic cells in the alveola of the lung. Excretion with the urine and feces was maximum on the first day after injection and on the fifth day the total amount reachsd about 1/3 of the injected dose. (Abstr. Japan. Med., 1: No. 1, 1960)