The Relationship of Bacterial Biofilms and Capsular Contracture in Breast Implants
Dragana Ajdić, Yasmina Zoghbi, David J. Gerth, Zubin J. Panthaki, Seth R. Thaller
Abstract
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Dragana Ajdić, Yasmina Zoghbi, David J. Gerth, Zubin J. Panthaki, Seth R. Thaller
Abstract
Open-access reader
Capsular contracture is a common sequelae of implant-based breast augmentation. Despite its prevalence, the etiology of capsular contracture remains controversial. Numerous studies have identified microbial biofilms on various implantable materials, including breast implants. Furthermore, biofilms have been implicated in subclinical infections associated with other surgical implants. In this review, we discuss microbial biofilms as a potential etiology of capsular contracture. The review also outlines the key diagnostic modalities available to identify the possible infectious agents found in biofilm, as well as available preventative and treatment measures.
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Capsular contracture is a common sequelae of implant-based breast augmentation. Despite its prevalence, the etiology of capsular contracture remains controversial. Numerous studies have identified microbial biofilms on various implantable materials, including breast implants. Furthermore, biofilms have been implicated in subclinical infections associated with other surgical implants. In this review, we discuss microbial biofilms as a potential etiology of capsular contracture. The review also outlines the key diagnostic modalities available to identify the possible infectious agents found in biofilm, as well as available preventative and treatment measures.
Key concepts: Capsular contracture, Medicine, Breast augmentation, Biofilm, Breast implant, Etiology, Subclinical infection, Contracture