Advance in treatment of rheumatoid arthritis.

Great progress has been made in the last decade in treatment of reumatoid arthritis(RA)by using biological technologies.However,there are several serious limitations of these therapies,such as the high expense,side-effects,and the requirement for repeated injections.Gene therapy for the treatment of RA is effective and stably on the specific target.Gene transfer vector,transfer cytokine gene therapy,tissue repair and gene therapy,therapy gene transfer for apoptosis gene were discussed in this paper.