2012•Journal of Traditional Chinese Veterinary MedicineRequires access
Effect of Forsythia active components on cell inflammation reaction model
Zhi Shiwei, SI Ningning, Long Li, An Xie, Yanhua Zhang, Ling Kuang
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Abstract
Objective: To study the effect of forsythia extract on cell model of anti-inflammation response.Methods: Forsythia extract was added to cell inflammation model at different concentration.The morphology change of the cells was observed and the light absorption value was determined using MTT method.Results: Cells in Phillyrin and Forsythia flavonoids control group showed no obvious changes on morphology,OD value displayed slightly lower than the blank control group.Almost all the cells of flavonoids control were broken.Cells in all colon bacillus control group present schizolysis and gathered into groups with a dose-effect relationship(P0.05).Conclusion: Forsythia extract showed protection on inflammatory cells compared with the same concentration of colon bacillus control(P0.05).The anti-inflammatory effect of Forsythia extract in the 100 μL concentration of colon bacillus filtrate was optimal.