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Stimulated Uptake of α-Aminoisobutyric Acid in Rat Liver Following Whole-Body γ-Irradiation

Zakariya K. Shihabi, Otto W. Neuhaus

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Abstract

Whole-body irradiation elicited an increase in14 C- AIB uptake by the rat liver with a concomitant decrease by kidney, muscle, spleen, and testes. Aminoethylisothiouronium (AET) and cysteamine (MEA) partially prevented these changes in the liver and kidney. The uptake of inulin and orotic acid by the liver was not affected by irradiation while that for32 P and algal hydrolysate was increased.

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What this paper is about

Whole-body irradiation elicited an increase in14 C- AIB uptake by the rat liver with a concomitant decrease by kidney, muscle, spleen, and testes. Aminoethylisothiouronium (AET) and cysteamine (MEA) partially prevented these changes in the liver and kidney. The uptake of inulin and orotic acid by the liver was not affected by irradiation while that for32 P and algal hydrolysate was increased.

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Available abstract

Whole-body irradiation elicited an increase in14 C- AIB uptake by the rat liver with a concomitant decrease by kidney, muscle, spleen, and testes. Aminoethylisothiouronium (AET) and cysteamine (MEA) partially prevented these changes in the liver and kidney. The uptake of inulin and orotic acid by the liver was not affected by irradiation while that for32 P and algal hydrolysate was increased.

Key concepts: Whole body irradiation, Aminoisobutyric acid, Chemistry, Irradiation, Whole body counting, Biochemistry, Radiochemistry, Amino acid

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Stimulated Uptake of α-Aminoisobutyric Acid in Rat Liver Following Whole-Body γ-Irradiation — Research Paper | ScholarLens