Effects of oral clonidine as pre-medication on blood pressure in patients under spinal anesthesia

: We have studied the effect of oral clonidine on Blood Pressure of the Patients under spinal anesthesia. For minor to moderate surgeries at Khatam-ul-anbia Hospital of Zahedan –Iran in 1380(2001). In this double –blinded , prospective , randomized study involving 50 patients who that divided in two 25-patients groups and the first groups reciveved oral clonidine 2 μg/kg drug 90 min prespinal anesthesia and the other group did not resived any drugs. 12% of group 1 patients had diastolic and systolic hypotension but at group 2 , 24% had systolic hypotension and 16% had diastolic hypotension after 10 min interval of spinal anesthesia. But there were no statistical difference between the two groups. Implications: Oral clonidine as premedication has no any effect on the blood pressure following spinal anesthesia, so we can use oral clonidine as premedication for its benefits.