2009Archives of Clinical Infectious DiseasesRequires access

FREQUENCY OF CRYPTOSPORIDIUM AND RISK FACTORS RELATED TO CRYPTOSPORIDIOSIS IN UNDER 5–YEAR OLD HOSPITALIZED CHILDREN DUE TO DIARRHEA

Bahman Khalili, Masoud Mardani

Open publisher page 16 citations

Abstract

Background: Recently Cryptosporidium has gained much attention as a clinically human pathogen in immunocompromised cases and young children. This study investigated frequency and risk factors related to cryptosporidiosis in under 5–year old children. Patients and methods: Stools were examined by ELISA method to detect Cryptosporidium surface antigen (CSA) using Remel Prospect Cryptosporidium (monoclonal) Microplate Assay. Stool samples were collected from children at admission and were kept at –70oC until examination. Data were collected by a standard questionnaire and analysed in Epi info 2002 software. Results: Of 171 children, 8(5%) were infected with Cryptosporidium. Most of the cases (6 cases) aged 2-12 months. Boys were more frequently infected than girls (p<0.05). Meanwhile, cryptosporidiosis was associated with less breastfeeding and lower birth weight (p<0.05). Conclusion: Results revealed that the frequency of cryptosporidiosis was similar to other parts of the world. Similarly, lower birth weight, less breast-feeding and male gender were associated with a higher frequency of cryptosporidiosis.

About this research paper

What this paper is about

Background: Recently Cryptosporidium has gained much attention as a clinically human pathogen in immunocompromised cases and young children. This study investigated frequency and risk factors related to cryptosporidiosis in under 5–year old children. Patients and methods: Stools were examined by ELISA method to detect Cryptosporidium surface antigen (CSA) using Remel Prospect Cryptosporidium (monoclonal) Microplate Assay. Stool samples were collected from children at admission and were kept at –70oC until examination. Data were collected by a standard questionnaire and analysed in Epi info 2002 software. Results: Of 171 children, 8(5%) were infected with Cryptosporidium. Most of the cases (6 cases) aged 2-12 months. Boys were more frequently infected than girls (p<0.05). Meanwhile, cryptosporidiosis was associated with less breastfeeding and lower birth weight (p<0.05). Conclusion: Results revealed that the frequency of cryptosporidiosis was similar to other parts of the world. Similarly, lower birth weight, less breast-feeding and male gender were associated with a higher frequency of cryptosporidiosis.

Why it matters

OpenAlex reports 16 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Background: Recently Cryptosporidium has gained much attention as a clinically human pathogen in immunocompromised cases and young children. This study investigated frequency and risk factors related to cryptosporidiosis in under 5–year old children. Patients and methods: Stools were examined by ELISA method to detect Cryptosporidium surface antigen (CSA) using Remel Prospect Cryptosporidium (monoclonal) Microplate Assay. Stool samples were collected from children at admission and were kept at –70oC until examination. Data were collected by a standard questionnaire and analysed in Epi info 2002 software. Results: Of 171 children, 8(5%) were infected with Cryptosporidium. Most of the cases (6 cases) aged 2-12 months. Boys were more frequently infected than girls (p<0.05). Meanwhile, cryptosporidiosis was associated with less breastfeeding and lower birth weight (p<0.05). Conclusion: Results revealed that the frequency of cryptosporidiosis was similar to other parts of the world. Similarly, lower birth weight, less breast-feeding and male gender were associated with a higher frequency of cryptosporidiosis.

Key concepts: Cryptosporidium, Breastfeeding, Diarrhea, Medicine, Breast feeding, Pediatrics, Internal medicine, Immunology

Related papers

Back to paper searchBrowse research topicsOriginal source
FREQUENCY OF CRYPTOSPORIDIUM AND RISK FACTORS RELATED TO CRYPTOSPORIDIOSIS IN UNDER 5–YEAR OLD HOSPITALIZED CHILDREN DUE TO DIARRHEA — Research Paper | ScholarLens