2011•Research Journal of Pharmacy and TechnologyRequires access

UV Spectrophotometric Estimation of Nitazoxanide in Tablet Dosage Form

Mahesh Mukund Deshpande, C S Soni, Veena Sanjay Kasture, S S Rohom, Suraj R. Chaudhari

Abstract

A simple, fast, precise method has been developed for estimation of nitazoxanide in tablet formulation. The sampling wavelengths selected for the drug was 346 nm. Standard stock solutions were prepared in dimethylformamide and the working solutions were prepared in phosphate buffer 7.4 PH. The linearity for the drug at the selected wavelengths lies between 5–25μg/ml for nitazoxanide. The recovery study was performed by using two different brands Nitacure and Nizonide of Nitazoxanide. The percentage Relative standard deviations for recovery study were well within the range.

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Key concepts: Nitazoxanide, Phosphate buffered saline, Mathematics, Dosage form, Relative standard deviation, Chromatography, Wavelength, Dimethylformamide