Angiolupoid Sarcoidosis: A Clinicopathological Study of a Distinct Variant of Cutaneous Sarcoidosis

Sarcoidosis is a mutisystem granulomatous disorder with protean manifestations ranging from self-limited skin lesins tointractable organ failure. Angiolupoid sarcoidosis is a rarely reported vari- ant of cutaneous sarcodosis characterized by erythematous plaques with superficial telangiectiasia on the face. Such disfiguring manifestation can cause profound social embarrassment. We reviewed the dermatological files in Chang Gung Memorial Hospital from 1985 to 2001. Eight cases with consis- tent features of angiolupoid sarcoidosis were identified. The clinical and pathological features, sys- temic associations, response of treatments, and course of the disease were reviewed retrospectively. The result of our study suggested that angiolupoid sarcoidosis is a distinct and significant subgroup of cutaneous sarcoidosis in Taiwan.