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[Fungal keratitis with annular infiltration and hypopyon].

De Gottrau P, LM Holbach, Naumann Go

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Abstract

Fungal keratitis is a rare disease in Northern Europe. We report the case of a 57-year-old female suffering from a paracentral corneal ulcer, following minor corneal trauma with a branch of a tree. Clinically, the ulcer was associated with a ring infiltrate and a hypopyon. Corneal smears and cultures were negative. As the corneal lesions and the hypopyon progressed despite maximal treatment, penetrating keratoplasty was performed on the assumption of a fungal origin. Histopathologic examination revealed pseudohyphae, morphologically compatible with a candida species. The clinical picture, its differential diagnosis and the diagnostic methods are discussed.

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What this paper is about

Fungal keratitis is a rare disease in Northern Europe. We report the case of a 57-year-old female suffering from a paracentral corneal ulcer, following minor corneal trauma with a branch of a tree. Clinically, the ulcer was associated with a ring infiltrate and a hypopyon. Corneal smears and cultures were negative. As the corneal lesions and the hypopyon progressed despite maximal treatment, penetrating keratoplasty was performed on the assumption of a fungal origin. Histopathologic examination revealed pseudohyphae, morphologically compatible with a candida species. The clinical picture, its differential diagnosis and the diagnostic methods are discussed.

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Available abstract

Fungal keratitis is a rare disease in Northern Europe. We report the case of a 57-year-old female suffering from a paracentral corneal ulcer, following minor corneal trauma with a branch of a tree. Clinically, the ulcer was associated with a ring infiltrate and a hypopyon. Corneal smears and cultures were negative. As the corneal lesions and the hypopyon progressed despite maximal treatment, penetrating keratoplasty was performed on the assumption of a fungal origin. Histopathologic examination revealed pseudohyphae, morphologically compatible with a candida species. The clinical picture, its differential diagnosis and the diagnostic methods are discussed.

Key concepts: Hypopyon, Fungal keratitis, corneal ulcer, Medicine, Keratitis, Corneal disease, Differential diagnosis, Mycosis

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