2000•PubMedRequires access
[Observation on specific IgG4 antibody of schistosomiasis patients before and after treatment].
Zheng Feng, Liwen Qiu, Y H Zhang, H Li
Open publisher page 1 citations
Abstract
OBJECTIVE: To observe the alteration of specific IgG4 antibody of schistosomiasis patients before and after treatment. METHODS: ELISA. RESULTS: The SEA-IgG4 and AWA-IgG4 positive rates of 27 schistosomiasis cases were 96.3% and 100%, respectively, their average OD values were 1.62 and 0.72. 6 months post treatment 18 cases were followed up, the positive rates were 94.4% and 100%, respectively, their average OD values were 1.06 and 0.56, respectively. 12 months post treatment all cases were followed up, the positive rates of SEA-IgG4 and AWA-IgG4 were 96.3% and 92.6%, respectively, their average OD values were 0.99 and 0.58, respectively. CONCLUSION: No obvious changes were found in the SEA-IgG4 and AWA-IgG4 positive rates of 27 schistosomiasis cases before and after treatment, whereas the antibody level of specific IgG4 was decreased.