Pentobarbital in refractory status epilepticus.
Richard S. Young, A. H. Ropper, David Hawkes, Marilyn G. Woods, P. Yohn
Abstract
Richard S. Young, A. H. Ropper, David Hawkes, Marilyn G. Woods, P. Yohn
Abstract
Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital. The efficacy of pentobarbital can be monitored at the bedside by electroencephalography. We report the clinical and electroencephalographic findings of two children who developed refractory tonic-clonic status epilepticus and responded to pentobarbital.
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Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital. The efficacy of pentobarbital can be monitored at the bedside by electroencephalography. We report the clinical and electroencephalographic findings of two children who developed refractory tonic-clonic status epilepticus and responded to pentobarbital.
Key concepts: Status epilepticus, Pentobarbital, Phenobarbital, Phenytoin, Anesthesia, Medicine, Refractory (planetary science), Tonic (physiology)