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Pentobarbital in refractory status epilepticus.

Richard S. Young, A. H. Ropper, David Hawkes, Marilyn G. Woods, P. Yohn

Open publisher page 22 citations

Abstract

Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital. The efficacy of pentobarbital can be monitored at the bedside by electroencephalography. We report the clinical and electroencephalographic findings of two children who developed refractory tonic-clonic status epilepticus and responded to pentobarbital.

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What this paper is about

Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital. The efficacy of pentobarbital can be monitored at the bedside by electroencephalography. We report the clinical and electroencephalographic findings of two children who developed refractory tonic-clonic status epilepticus and responded to pentobarbital.

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OpenAlex reports 22 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital. The efficacy of pentobarbital can be monitored at the bedside by electroencephalography. We report the clinical and electroencephalographic findings of two children who developed refractory tonic-clonic status epilepticus and responded to pentobarbital.

Key concepts: Status epilepticus, Pentobarbital, Phenobarbital, Phenytoin, Anesthesia, Medicine, Refractory (planetary science), Tonic (physiology)

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