[Intrahepatic cholestasis of pregnancy, an unpredictable fetal risk: report of a case and review of the literature].

This is a clinical case of intrahepatic cholestasis of pregnancy that developed fetal death few hours after a reactive non-stress test. A 35 year old woman who suffered intrahepatic cholestasis in two previous pregnancies with good outcome. In her last pregnancy she had again intrahepatic cholestasis with abnormal liver tests. The clinical evolution, as well as electronic fetal heart monitoring and ultrasonographic evolution were all normal except for the fetal growth that was restricted, but symmetric. At 35 4/7 weeks of gestation she developed prodromic uterine contractions and a non-stress test was normal. However, 8 hours later the patient returned for reexamination and the fetus was found dead and at birth was a symmetrically small male baby. The fetus' genetic study and placenta's histological study were both normal. The patient cholestasis was resolved few weeks later.