Ethosomes: Novel Approach in Transdermal Drug Delivery System

Transdermal drug delivery system is emerging system as compaired to oral and parentral.in TDDS, patch system was developed to control the release of drug. Conventional transdermal drug delivery system achieved advantages over the oral and parenteral. Consequently a number of vesicular drug delivery systems such as liposomes, niosomes were been developed as novel transdermal drug delivery system. Firstly, it delivers the drug at a rate directed by the needs of the body, over the period of treatment. Secondly, it channel the active entity to the site of action. However, TDDS has limited market success due to the barrier properties of the Stratum Corneum and stability of formulation. ethosomes is better achievement in vesicular drug delivery system, helpful to achieve goal needed by NTDDS. Ethosomes are noninvasive delivery carriers that enable drugs to reach the deep skin layers and/or the systemic circulation. This review focus on introduction, mechanism of penetration, method of preparation, methods of characterization and application in the field.