2006•Korean Journal of AnesthesiologyOpen access
Effect of Nitrous Oxide on Bispectral Index during Sevoflurane Anesthesia
Kyoung Hun Kim, Yun Jeong Choi, Jae Hang Shim, Woo Jae Jeon, Sang Yoon Cho, Woo Jong Shin, Jong Hoon Yeom
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Abstract
Background: Nitrous oxide is generally avoided in order to prevent either hypoxia or graft dislodgment during tympanoplasty. The aim of this study was to investigate the effect of nitrous oxide on the bispectral index during sevoflurane anesthesia at the anesthetic dose. Methods: The bispectral index was continually measured during nitrous oxide-oxygen-sevoflurane anesthesia, discontinuation of nitrous oxide and the reintroduction of nitrous oxide. Results: The bispectral index of nitrous oxide-oxygen-sevoflurane anesthesia increased after discontinuing the nitrous oxide and decreased after its reintroduction. Conclusions: Nitrous oxide decreased the bispectral index of nitrous oxide-oxygen-sevoflurane anesthesia compared with oxygen-sevoflurane anesthesia at the anesthetic dose.