2015URMIA MEDICAL JOURNALOpen access

THE ACCURACY OF INTRAOPERATIVE SCRAPE CYTOLOGY IN DIAGNOSIS OF OVARIAN TUMORS

Fariba Abbasi, Farahnaz Noroozinia, Amin Moradi, Sima Oshnoi

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Abstract

Intra-operative diagnosis of ovarian tumors is mandatory because various types of tumors with different optimal management are seen in ovary. This study was done to determine the accuracy of scrape cytology in intraoperative diagnosis of ovarian tumors. Materials & Methods: In this prospective study, we studied scrape cytology smears of 75 consecutive ovarian tumors received in department of pathology during September 2010 to September 2012. Then, we compared the results with frozen section and permanent section results in each case. Accuracy, sensitivity, specificity, positive and negative predictive values of both methods were calculated Results: Overall accuracy of scrape cytology was 96% and of frozen section 97.34%. Sensitivity, specificity, positive and negative predictive values of scrape cytology were 92.30%, 96.77%, 85.71% and 98.36%, respectively. These figures were 92.30%, 98.38%, 92.30% and 98.38% for frozen section. Conclusion: It seems that scrape cytology can be used as a simple inexpensive method for intraoperative diagnosis of ovarian tumors as complementary or an alternative to frozen section, however, combination of both methods is more reliable

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Intra-operative diagnosis of ovarian tumors is mandatory because various types of tumors with different optimal management are seen in ovary. This study was done to determine the accuracy of scrape cytology in intraoperative diagnosis of ovarian tumors. Materials & Methods: In this prospective study, we studied scrape cytology smears of 75 consecutive ovarian tumors received in department of pathology during September 2010 to September 2012. Then, we compared the results with frozen section and permanent section results in each case. Accuracy, sensitivity, specificity, positive and negative predictive values of both methods were calculated Results: Overall accuracy of scrape cytology was 96% and of frozen section 97.34%. Sensitivity, specificity, positive and negative predictive values of scrape cytology were 92.30%, 96.77%, 85.71% and 98.36%, respectively. These figures were 92.30%, 98.38%, 92.30% and 98.38% for frozen section. Conclusion: It seems that scrape cytology can be used as a simple inexpensive method for intraoperative diagnosis of ovarian tumors as complementary or an alternative to frozen section, however, combination of both methods is more reliable

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Available abstract

Intra-operative diagnosis of ovarian tumors is mandatory because various types of tumors with different optimal management are seen in ovary. This study was done to determine the accuracy of scrape cytology in intraoperative diagnosis of ovarian tumors. Materials & Methods: In this prospective study, we studied scrape cytology smears of 75 consecutive ovarian tumors received in department of pathology during September 2010 to September 2012. Then, we compared the results with frozen section and permanent section results in each case. Accuracy, sensitivity, specificity, positive and negative predictive values of both methods were calculated Results: Overall accuracy of scrape cytology was 96% and of frozen section 97.34%. Sensitivity, specificity, positive and negative predictive values of scrape cytology were 92.30%, 96.77%, 85.71% and 98.36%, respectively. These figures were 92.30%, 98.38%, 92.30% and 98.38% for frozen section. Conclusion: It seems that scrape cytology can be used as a simple inexpensive method for intraoperative diagnosis of ovarian tumors as complementary or an alternative to frozen section, however, combination of both methods is more reliable

Key concepts: Frozen section procedure, Cytology, Medicine, Ovary, Diagnostic accuracy, Fine needle aspiration cytology, Positive predicative value, Prospective cohort study

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