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2016•BMJOpen access

Exercise induced bronchoconstriction in adults: evidence based diagnosis and management

James M. Smoliga, Pnina Weiss, Kenneth W. Rundell

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Abstract

This is comment on: Smoliga JM, Weiss P, Rundell KW. Exercise induced bronchoconstriction in adults: evidence based diagnosis and management.BMJ. 2016 Jan 13;352:h6951.https://pubmed.ncbi.nlm.nih.gov/26762594 Smoliga, Weiss and Rundell reviewed exercise-induced bronchoconstriction (EIB) and implied in their title that they covered evidence-based managements of EIB. EBM requires that the literature searches should be thorough, and RCTs and systematic reviews should be the primary focus of the searches. There are 3 RCTs on vitamin C and EIB and the pooled relative effect estimate indicates a 48% reduction (95% CI 33% to 64%) in the postexercise FEV1 decline when vitamin C was administered before exercise [1,2]. These findings were not mentioned by Smoliga et al.

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What this paper is about

This is comment on: Smoliga JM, Weiss P, Rundell KW. Exercise induced bronchoconstriction in adults: evidence based diagnosis and management.BMJ. 2016 Jan 13;352:h6951.https://pubmed.ncbi.nlm.nih.gov/26762594 Smoliga, Weiss and Rundell reviewed exercise-induced bronchoconstriction (EIB) and implied in their title that they covered evidence-based managements of EIB. EBM requires that the literature searches should be thorough, and RCTs and systematic reviews should be the primary focus of the searches. There are 3 RCTs on vitamin C and EIB and the pooled relative effect estimate indicates a 48% reduction (95% CI 33% to 64%) in the postexercise FEV1 decline when vitamin C was administered before exercise [1,2]. These findings were not mentioned by Smoliga et al.

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Available abstract

This is comment on: Smoliga JM, Weiss P, Rundell KW. Exercise induced bronchoconstriction in adults: evidence based diagnosis and management.BMJ. 2016 Jan 13;352:h6951.https://pubmed.ncbi.nlm.nih.gov/26762594 Smoliga, Weiss and Rundell reviewed exercise-induced bronchoconstriction (EIB) and implied in their title that they covered evidence-based managements of EIB. EBM requires that the literature searches should be thorough, and RCTs and systematic reviews should be the primary focus of the searches. There are 3 RCTs on vitamin C and EIB and the pooled relative effect estimate indicates a 48% reduction (95% CI 33% to 64%) in the postexercise FEV1 decline when vitamin C was administered before exercise [1,2]. These findings were not mentioned by Smoliga et al.

Key concepts: Bronchoconstriction, Medicine, Asthma, Physical therapy, Data science, Computer science, Intensive care medicine, Internal medicine

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