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2010•PubMedOpen access

Physico-Phytochemical investigation and Anti-inflammatory screening of Capsicum annum L. and Hemidesmus indicus (Linn.) R. Br.

K Vijayalakshmi, Rajkumar Shyamala, V. Thirumurugan, Mathur Gopalakrishnan Sethuraman, S Rajan, Shrishailappa Badami, Pulok Kumar Mukherjee

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Abstract

Capsicum annum L. (Family: Solanaceae) and Hemidesmus indicus (Linn.) R.Br. (Family: Asclepiadaceae) are commonly used in Tamilnadufor treating various ailments in the native system of medicine. The hydroalcoholic extracts of both plants at dose level of 100 mg/kg body weight showed demonstrable anti-inflammatory activity in the carrageenan-induced hind paw model in rats. Nevertheless, the overall anti-inflammatory activity exhibited by the extracts are found to be less as compared with that of standard drug Indometacin. Preliminary physico-phytochemical analysis of the plants in question were attempted. The results are highlighted and discussed.

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What this paper is about

Capsicum annum L. (Family: Solanaceae) and Hemidesmus indicus (Linn.) R.Br. (Family: Asclepiadaceae) are commonly used in Tamilnadufor treating various ailments in the native system of medicine. The hydroalcoholic extracts of both plants at dose level of 100 mg/kg body weight showed demonstrable anti-inflammatory activity in the carrageenan-induced hind paw model in rats. Nevertheless, the overall anti-inflammatory activity exhibited by the extracts are found to be less as compared with that of standard drug Indometacin. Preliminary physico-phytochemical analysis of the plants in question were attempted. The results are highlighted and discussed.

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Available abstract

Capsicum annum L. (Family: Solanaceae) and Hemidesmus indicus (Linn.) R.Br. (Family: Asclepiadaceae) are commonly used in Tamilnadufor treating various ailments in the native system of medicine. The hydroalcoholic extracts of both plants at dose level of 100 mg/kg body weight showed demonstrable anti-inflammatory activity in the carrageenan-induced hind paw model in rats. Nevertheless, the overall anti-inflammatory activity exhibited by the extracts are found to be less as compared with that of standard drug Indometacin. Preliminary physico-phytochemical analysis of the plants in question were attempted. The results are highlighted and discussed.

Key concepts: Phytochemical, Traditional medicine, Anti-inflammatory, Carrageenan, Indometacin, Medicine, Chemistry, Pharmacology

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Physico-Phytochemical investigation and Anti-inflammatory screening of Capsicum annum L. and Hemidesmus indicus (Linn.) R. Br. — Research Paper | ScholarLens