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Two Common Drugs Promote Remyelination in Demyelinating Disease of Mice

Anthony L. Komaroff

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Abstract

In multiple sclerosis (MS) and other demyelinating diseases, autoimmune attacks lead to demyelination. Approved therapies for MS target this immune attack and prevent further demyelination. An alternative approach to treating demyelination would be to encourage remyelination. Oligodendrocytes in the central nervous system have the ability to promote remyelination; however, in humans (and other mammals), remyelination …

About this research paper

What this paper is about

In multiple sclerosis (MS) and other demyelinating diseases, autoimmune attacks lead to demyelination. Approved therapies for MS target this immune attack and prevent further demyelination. An alternative approach to treating demyelination would be to encourage remyelination. Oligodendrocytes in the central nervous system have the ability to promote remyelination; however, in humans (and other mammals), remyelination …

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Available abstract

In multiple sclerosis (MS) and other demyelinating diseases, autoimmune attacks lead to demyelination. Approved therapies for MS target this immune attack and prevent further demyelination. An alternative approach to treating demyelination would be to encourage remyelination. Oligodendrocytes in the central nervous system have the ability to promote remyelination; however, in humans (and other mammals), remyelination …

Key concepts: Remyelination, Multiple sclerosis, Demyelinating disease, Medicine, Central nervous system, Disease, Neuroscience, Demyelinating Disorder

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