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2015•Intensive Care Medicine ExperimentalOpen access

Early administration of low dose norepinephrine for the prevention of organ dysfunctions in patients with sepsis

MK Arslantas, Fethi Gül, Alper Kararmaz, F Sungur, H.O Ayanoglu, İsmail Cinel

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Abstract

The importance of vasopressors in achieving the mean arterial pressure target in the early resuscitation of septic shock has been demonstrated and sepsis has been recently defined as a systemic response to infection with the presence of some degree of organ dysfunction [ 1 , 2 ]. However, timing of norepinephrine (NE) for the prevention of organ dysfunctions in sepsis has not been investigated.

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What this paper is about

The importance of vasopressors in achieving the mean arterial pressure target in the early resuscitation of septic shock has been demonstrated and sepsis has been recently defined as a systemic response to infection with the presence of some degree of organ dysfunction [ 1 , 2 ]. However, timing of norepinephrine (NE) for the prevention of organ dysfunctions in sepsis has not been investigated.

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Available abstract

The importance of vasopressors in achieving the mean arterial pressure target in the early resuscitation of septic shock has been demonstrated and sepsis has been recently defined as a systemic response to infection with the presence of some degree of organ dysfunction [ 1 , 2 ]. However, timing of norepinephrine (NE) for the prevention of organ dysfunctions in sepsis has not been investigated.

Key concepts: Medicine, Sepsis, Organ dysfunction, Norepinephrine, Septic shock, Resuscitation, Intensive care medicine, Shock (circulatory)

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