Histopathological microscopical and ultramicroscopical studies on changes of uterus and ovary of patients in canine pyometra

Microscopical and ultramicroscopical structure of the uterus and ovary from 96 canine pyometra cases were observed with microtomy and light microscopy and transmission electron microscopy to discuss the etiology of canine pyometra.The results showed that there were histophathological changes of endometrial glads with various degrees of cystic endometrial hyperplasia(CEH)and inflammation and retained or cystoid corpus luteum in ovary in most patients.Thickness of endometrium was observed in most opened-cervix cases.Atrophy of endometrium and very thin wall of uterus were seen in most closed-cervix cases.When CEH occured in the endometrial gland in closed-cervix cases,pathological changes such as spuamous metaplasia and adenomatoid lesion were found in the epithelium of endometrium.In addition,the macroscopical,microscopical and ultramicroscopical histopathological changes of the ovary and uterus in closed-cervix cases was more obvious than those of opened-cervix cases.