Effect of enzyme supplementation on the graded replacement of fish meal in broiler diet

Broiler starter diet containing 14 percent fish meal were replaced by sesame cake protein at 50, 75, 87.5 and 100 percent levels with or without supplementation of enzyme combination. Synthetic lysine and methionine were incorporated to the optimum levels. Six weeks growth study showed that the gain and feed efficiency of the groups receiving diets with 50 and 75 percent replacement of fish meal with enzyme were comparable with the control diet. However, with the higher replacement of fish meal revealed significantly (P < 0.01) low body weight gain and feed efficiency. The condition did not improve even with the different combinations of vegetable protein. Histopathological examinations of liver, kidney, lung and thyroid gland revealed that there were characteristic changes in the total vegetable protein fed group where in rape seed was present.