Estrogen and the Heart
Jay M. Sullivan
Abstract
Jay M. Sullivan
Abstract
Premenopausal women have far fewer heart attacks than comparably aged men, and the incidence of cardiovascular disease increases after menopause: These facts were first commented upon in the 1930s. Since then, over 35 observational studies have reported that the total mortality rate and cardiovascular events rates of postmenopausal women who chose to take estrogen replacement therapy (ERT) is about 40–50% lower than women who go without hormone replacement ( 1 ). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Premenopausal women have far fewer heart attacks than comparably aged men, and the incidence of cardiovascular disease increases after menopause: These facts were first commented upon in the 1930s. Since then, over 35 observational studies have reported that the total mortality rate and cardiovascular events rates of postmenopausal women who chose to take estrogen replacement therapy (ERT) is about 40–50% lower than women who go without hormone replacement ( 1 ). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Key concepts: Estrogen, Menopause, Medicine, Observational study, Hormone replacement therapy (female-to-male), Estrogen replacement therapy, Hormone replacement, Incidence (geometry)