A 6% benzoyl peroxide foaming cloth cleanser used in the treatment of acne vulgaris: aesthetic characteristics, patient preference considerations, and impact on compliance with treatment.

OBJECTIVE: The study was conducted to evaluate the product attributes of a new benzoyl peroxide-containing foaming cloth cleanser and to compare the overall patient satisfaction of this product with two currently available benzoyl peroxide acne products (6% benzoyl peroxide cleanser and 4% benzoyl peroxide wash). DESIGN: This was a randomized, single-blind study. SETTING: Two clinical trial sites. PARTICIPANTS: Male and female subjects (N=193) aged 17 to 30 years with a history of acne vulgaris were enrolled. MEASURES: Subjects initially cleansed their face with the benzoyl peroxide foaming cloth and then completed a product-attribute survey. Following an interval of five minutes or more, subjects cleansed their face again using one of two randomly assigned comparator benzoyl peroxide-containing cleansing products and then completed a comparative survey. Survey results were tabulated and a top-two box analysis was performed. RESULTS: Following the use of the benzoyl peroxide-containing foaming cloth, 94 percent of the product-attribute responses were positive (p</=0.05). With respect to convenience, usability, and cosmetic elegance, the majority of subjects indicated a preference for the benzoyl peroxide foaming cloth compared to the 6% benzoyl peroxide cleanser and 4% benzoyl peroxide wash (for each, p</=0.05). There were no reports of adverse events. CONCLUSION: These attributes supporting preference for the benzoyl peroxide foaming cloth cleanser may improve patient satisfaction with topical acne treatment resulting in improved patient compliance. (J Clin Aesthetic Dermatol. 2009;2(7):26-29.).