2015•Translational gastrointestinal cancerRequires access

Can Milan criteria be expanded effectively for liver transplantation in patients with HCC

Federico Aucejo, Richard D. Kim

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Abstract

The Milan hepatocellular carcinoma (HCC) criteria emerged as the worldwide standard criteria for liver transplant eligibility. However, it has been observed that selected patients with more advanced tumor stage can achieve equivalent outcomes. A large retrospective analysis from Xu et al . comparing the Hangzhou HCC criteria with other expanded criteria suggests the Hangzhou criteria can offer the broadest application of liver transplantation for HCC patients without detriment in survival.

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What this paper is about

The Milan hepatocellular carcinoma (HCC) criteria emerged as the worldwide standard criteria for liver transplant eligibility. However, it has been observed that selected patients with more advanced tumor stage can achieve equivalent outcomes. A large retrospective analysis from Xu et al . comparing the Hangzhou HCC criteria with other expanded criteria suggests the Hangzhou criteria can offer the broadest application of liver transplantation for HCC patients without detriment in survival.

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Available abstract

The Milan hepatocellular carcinoma (HCC) criteria emerged as the worldwide standard criteria for liver transplant eligibility. However, it has been observed that selected patients with more advanced tumor stage can achieve equivalent outcomes. A large retrospective analysis from Xu et al . comparing the Hangzhou HCC criteria with other expanded criteria suggests the Hangzhou criteria can offer the broadest application of liver transplantation for HCC patients without detriment in survival.

Key concepts: Milan criteria, Medicine, Hepatocellular carcinoma, Liver transplantation, Internal medicine, Stage (stratigraphy), Overall survival, Retrospective cohort study

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