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Chromosome-exchange Aberrations in Human Lymphocytes

Amos Norman, M.S. Sasaki

Open publisher page 94 citations

Abstract

SummaryThe probability of finding a given chromosome in a dicentric is directly proportional to the length of that chromosome at interphase, but not to the length of the early replicating portion of the interphase chromosome or to its length at metaphase. The number of dicentric chromosomes and centric rings per cell is limited primarily by the number of centromeres. These results are consistent with the assumption that every chromosome break is a site for chromosome-exchange.

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SummaryThe probability of finding a given chromosome in a dicentric is directly proportional to the length of that chromosome at interphase, but not to the length of the early replicating portion of the interphase chromosome or to its length at metaphase. The number of dicentric chromosomes and centric rings per cell is limited primarily by the number of centromeres. These results are consistent with the assumption that every chromosome break is a site for chromosome-exchange.

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OpenAlex reports 94 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

SummaryThe probability of finding a given chromosome in a dicentric is directly proportional to the length of that chromosome at interphase, but not to the length of the early replicating portion of the interphase chromosome or to its length at metaphase. The number of dicentric chromosomes and centric rings per cell is limited primarily by the number of centromeres. These results are consistent with the assumption that every chromosome break is a site for chromosome-exchange.

Key concepts: Dicentric chromosome, Chromosome, Interphase, Centromere, Metaphase, Genetics, Biology, Chromosome 22

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