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Probiotics in Antibiotic-Associated Diarrhea and Clostridium difficile Infection

Hania Szajewska

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Abstract

Antibiotic-associated diarrhea (AAD) is a common pediatric disorder. This chapter summarizes the available evidence on the efficacy of probiotics in children in the prevention and treatment of any diarrhea associated with the use of antibiotics and that was caused by Clostridium difficile . Results emerging from pediatric trials provide evidence of a moderate beneficial effect of selected probiotic microorganisms, such as Saccharomyces boulardii or Lactobacillus GG, in the prevention of AAD in children.

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What this paper is about

Antibiotic-associated diarrhea (AAD) is a common pediatric disorder. This chapter summarizes the available evidence on the efficacy of probiotics in children in the prevention and treatment of any diarrhea associated with the use of antibiotics and that was caused by Clostridium difficile . Results emerging from pediatric trials provide evidence of a moderate beneficial effect of selected probiotic microorganisms, such as Saccharomyces boulardii or Lactobacillus GG, in the prevention of AAD in children.

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Available abstract

Antibiotic-associated diarrhea (AAD) is a common pediatric disorder. This chapter summarizes the available evidence on the efficacy of probiotics in children in the prevention and treatment of any diarrhea associated with the use of antibiotics and that was caused by Clostridium difficile . Results emerging from pediatric trials provide evidence of a moderate beneficial effect of selected probiotic microorganisms, such as Saccharomyces boulardii or Lactobacillus GG, in the prevention of AAD in children.

Key concepts: Saccharomyces boulardii, Antibiotic-associated diarrhea, Diarrhea, Clostridium difficile, Probiotic, Antibiotics, Medicine, C difficile

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