2015Case Reports in NeurologyOpen access

Cerebral Amyloid Angiopathy Presenting with Synchronous Bilateral Intracerebral Macrohemorrhages

Jeremy S. Shelton, L. Taylor Davis, R. Stokes Peebles, Benjamin F. Tillman, Bret C. Mobley

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Abstract

Cerebral amyloid angiopathy (CAA) is the deposition of amyloid proteins in the cerebrovasculature, which can lead to intracerebral hemorrhage. Intracerebral hemorrhage in CAA often presents with microhemorrhages and, less frequently, with more devastating macrohemorrhages. We present a case of CAA-related synchronous bilateral intracerebral macrohemorrhage which, to our knowledge, has yet to be reported in the literature, and postulate its relationship to antiplatelet therapy and transient elevations in blood pressure.

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Cerebral amyloid angiopathy (CAA) is the deposition of amyloid proteins in the cerebrovasculature, which can lead to intracerebral hemorrhage. Intracerebral hemorrhage in CAA often presents with microhemorrhages and, less frequently, with more devastating macrohemorrhages. We present a case of CAA-related synchronous bilateral intracerebral macrohemorrhage which, to our knowledge, has yet to be reported in the literature, and postulate its relationship to antiplatelet therapy and transient elevations in blood pressure.

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Available abstract

Cerebral amyloid angiopathy (CAA) is the deposition of amyloid proteins in the cerebrovasculature, which can lead to intracerebral hemorrhage. Intracerebral hemorrhage in CAA often presents with microhemorrhages and, less frequently, with more devastating macrohemorrhages. We present a case of CAA-related synchronous bilateral intracerebral macrohemorrhage which, to our knowledge, has yet to be reported in the literature, and postulate its relationship to antiplatelet therapy and transient elevations in blood pressure.

Key concepts: Cerebral amyloid angiopathy, Intracerebral hemorrhage, Medicine, Amyloid (mycology), Angiopathy, Pathology, Neuroscience, Internal medicine

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