Cream Containing Acacia Bark Extract Significantly Reduces Skin Sebum Content in Healthy Volunteers

This study presents sebum reduction in volunteers’ cheeks when applied a cream containing Acacia bark extract analyzed by non-invasive instrument Sebumeter. A cream containing Acacia nilotica bark extract (3%) versus base was applied in single blinded study twice daily to the cheeks for a period of 12 weeks. The instrumental measurements were carried out with Sebumeter under a draught-free room, with controlled temperature (18.0–20.6°C) and relative humidity (55–65%). Active cream showed a significant decrease in skin sebum and base showed insignificant results when applied ANOVA. This study indicates that incorporation of Acacia bark extract in creams significantly reduces sebum secretion in vivo and can be used for the topical treatment of oily skin in humans.