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Eosinophilic granuloma of skull in a 7 year child: Diagnosed on fine needle aspiration cytology İnce iğne aspirasyon biyopsisi ile kafatasinda eozinofilik granülom tanisi alan 7 yaşinda çocuk olgu

Ruchi Agarwal, Parveen Rana, Amrita Duhan, Sanjay Verma, Rajnish Kalra, Ruchi Agarwal, P. Rana, Amrita Duhan, Sanjay Verma, K. Rajnish

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Abstract

Eosinophilic granuloma is a rare bone tumor, representing less than 1% of all bone tumors. Eosinophilic granuloma is the benign form of three clinical variants of Langerhans cell histiocytosis (LCH). It commonly affects children and young adults, particularly males. The characteristic cytologic features of eosinophilic granuloma include langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils and lymphocytes. We are reporting a case of eosinophilic granuloma of skull in a 7 years child diagnosed on fine needle aspiration cytology (FNAC). We here by emphasize the importance of rapid and reliable diagnosis of LCH by FNAC and the need to consider the possibility of LCH in the differential diagnosis of a slide showing a large number of histiocytes and eosinophils.

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Eosinophilic granuloma is a rare bone tumor, representing less than 1% of all bone tumors. Eosinophilic granuloma is the benign form of three clinical variants of Langerhans cell histiocytosis (LCH). It commonly affects children and young adults, particularly males. The characteristic cytologic features of eosinophilic granuloma include langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils and lymphocytes. We are reporting a case of eosinophilic granuloma of skull in a 7 years child diagnosed on fine needle aspiration cytology (FNAC). We here by emphasize the importance of rapid and reliable diagnosis of LCH by FNAC and the need to consider the possibility of LCH in the differential diagnosis of a slide showing a large number of histiocytes and eosinophils.

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Available abstract

Eosinophilic granuloma is a rare bone tumor, representing less than 1% of all bone tumors. Eosinophilic granuloma is the benign form of three clinical variants of Langerhans cell histiocytosis (LCH). It commonly affects children and young adults, particularly males. The characteristic cytologic features of eosinophilic granuloma include langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils and lymphocytes. We are reporting a case of eosinophilic granuloma of skull in a 7 years child diagnosed on fine needle aspiration cytology (FNAC). We here by emphasize the importance of rapid and reliable diagnosis of LCH by FNAC and the need to consider the possibility of LCH in the differential diagnosis of a slide showing a large number of histiocytes and eosinophils.

Key concepts: Eosinophilic granuloma, Langerhans cell histiocytosis, Histiocyte, Medicine, Pathology, Histiocytosis X, Eosinophilic, Cytology

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Eosinophilic granuloma of skull in a 7 year child: Diagnosed on fine needle aspiration cytology İnce iğne aspirasyon biyopsisi ile kafatasinda eozinofilik granülom tanisi alan 7 yaşinda çocuk olgu — Research Paper | ScholarLens