Effect of Water Extract Prepared from Green Tea, Black Tea and Cinnamon on Obese Rats Suffering from Diabetes
Manal A. Hasanein, Soha H. Abdel Gawad, Ashraf A. Abd El-Megeid
Abstract
Manal A. Hasanein, Soha H. Abdel Gawad, Ashraf A. Abd El-Megeid
Abstract
Abstract: Recently, considerable attention has been focused on dietary and medicinal antioxidants that inhibit or retard diseases caused by oxidative processes. The active components and polyphenols of green or black tea and cinnamon have antioxidant properties. The present work was carried out to study the potential effect of some doses of water extract which prepared from green tea, black tea and cinnamon on obese rats suffering from diabetes. Water extracts of green tea, black tea and cinnammon were prepared with traditional methods. Sixty six male albino rats (Sprague Dawley Strain) weighting an average of (125±5g) used in this study. The rats were divided into two main groups. The first main group (6 rats) was fed on basal diet as a (control negative group). The second main group (n = 60) fed on high fat diet for 4 weeks to induced obesity. After this period we made sure of induction, the second main group injected with (150 mg aloxane/kg body weight) to induce hyperglycemia. Then, this group was divided into ten subgroups (n=6) as a following: Subgroup (1) fed on high fat diet, as a control positive group. Subgroup (2, 3 and 4) fed on high fat diet and treated daily with 1, 2 and 4 ml water extract prepared from green tea / each rat/day/day. Subgroup (5, 6 and 7) fed on high fat diet and treated daily with 1, 2 and 4 ml water extract prepared from black tea/each rat. Subgroup (8. 9 and 10) fed on high fat diet and treated daily with 1, 2 and 4 ml water extract prepared from cinnamon/each rat/day. The results revealed that, final weight, body weight gain %, liver weight /body weight % and serum (glucose, cholesterol,
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Abstract: Recently, considerable attention has been focused on dietary and medicinal antioxidants that inhibit or retard diseases caused by oxidative processes. The active components and polyphenols of green or black tea and cinnamon have antioxidant properties. The present work was carried out to study the potential effect of some doses of water extract which prepared from green tea, black tea and cinnamon on obese rats suffering from diabetes. Water extracts of green tea, black tea and cinnammon were prepared with traditional methods. Sixty six male albino rats (Sprague Dawley Strain) weighting an average of (125±5g) used in this study. The rats were divided into two main groups. The first main group (6 rats) was fed on basal diet as a (control negative group). The second main group (n = 60) fed on high fat diet for 4 weeks to induced obesity. After this period we made sure of induction, the second main group injected with (150 mg aloxane/kg body weight) to induce hyperglycemia. Then, this group was divided into ten subgroups (n=6) as a following: Subgroup (1) fed on high fat diet, as a control positive group. Subgroup (2, 3 and 4) fed on high fat diet and treated daily with 1, 2 and 4 ml water extract prepared from green tea / each rat/day/day. Subgroup (5, 6 and 7) fed on high fat diet and treated daily with 1, 2 and 4 ml water extract prepared from black tea/each rat. Subgroup (8. 9 and 10) fed on high fat diet and treated daily with 1, 2 and 4 ml water extract prepared from cinnamon/each rat/day. The results revealed that, final weight, body weight gain %, liver weight /body weight % and serum (glucose, cholesterol,
Key concepts: Green tea, Green tea extract, Black tea, Antioxidant, Obesity, Polyphenol, Diabetes mellitus, Traditional medicine