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[Our experience in using liquid based cytology in cervical screening (LBC)].

A Tsonev, S Ivanov, E Kovachev, Yavor Kornovski, E Ismail

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Abstract

AIM: Our aim is to summarize our experience in screening for cervical cancer using liquid-based cytology system and the Bethesda system. MATERIAL AND METHODS: We did a clinical study of 92 patients, aimed to summarize the results of liquid-based cytology based on various criteria such as specificity, sensitivity, positive and false negative results. All patients had conventional Pap smear as well. RESULTS: The better results stand out of the LBC, mainly due to the reduced number of unsatisfactory results and higher specificity and sensitivity for low-grade lesions--LSIL. There is better standardization of samples, because of the automation of the process. The method is much better quality and more economical. CONCLUSION: The results obtained by us confirm the diagnostic quality and efficiency of the method, so we offer routine use in Bulgaria, as it is in some developed countries.

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What this paper is about

AIM: Our aim is to summarize our experience in screening for cervical cancer using liquid-based cytology system and the Bethesda system. MATERIAL AND METHODS: We did a clinical study of 92 patients, aimed to summarize the results of liquid-based cytology based on various criteria such as specificity, sensitivity, positive and false negative results. All patients had conventional Pap smear as well. RESULTS: The better results stand out of the LBC, mainly due to the reduced number of unsatisfactory results and higher specificity and sensitivity for low-grade lesions--LSIL. There is better standardization of samples, because of the automation of the process. The method is much better quality and more economical. CONCLUSION: The results obtained by us confirm the diagnostic quality and efficiency of the method, so we offer routine use in Bulgaria, as it is in some developed countries.

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Available abstract

AIM: Our aim is to summarize our experience in screening for cervical cancer using liquid-based cytology system and the Bethesda system. MATERIAL AND METHODS: We did a clinical study of 92 patients, aimed to summarize the results of liquid-based cytology based on various criteria such as specificity, sensitivity, positive and false negative results. All patients had conventional Pap smear as well. RESULTS: The better results stand out of the LBC, mainly due to the reduced number of unsatisfactory results and higher specificity and sensitivity for low-grade lesions--LSIL. There is better standardization of samples, because of the automation of the process. The method is much better quality and more economical. CONCLUSION: The results obtained by us confirm the diagnostic quality and efficiency of the method, so we offer routine use in Bulgaria, as it is in some developed countries.

Key concepts: Liquid-based cytology, Bethesda system, Standardization, Medicine, Cytology, Medical physics, Cervical cancer screening, Gynecology

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